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what is tablet capping and how to it

Tablet Capping

Definition: The term is used when either the upper or lower part of the tablet separates horizontally either partially away from the main body or completely and forms a cap when ejected from the press or during the handling process.

Cause: This happens when air is trapped during the compression stage and when the tablet expands after being ejected from the die.

Tablet Binders what you need to know

Tablet Binders

Tablet binders are one of the most essential elements in the formulation of a tablet. Because they promote cohesiveness, the binders, also called adhesives, help the other ingredients in a tablet to mix together. Tablet binders are used to turn powder to granules; this is achieved through the process of granulation. During granulation, powder substances are accumulated to form larger particles called granules.

What Are Soft and Hard Gelatin Capsules?

What Are Soft and Hard Gelatin Capsules?

Capsules are popular and commonly used in the pharmaceutical industry, not only is it easy to manufacturer but it do not need any complex formulation unlike other drug containers.

What is a single station tablet press and how does it work?

What is a single station tablet press and how does it work?

A single station tablet press is a simple mechanical machine that can be used to compress powder into tablets that are uniform in size, shape and weight. The machine is used for low-volume production of tablets for a wide range of applications from cosmetics and pharmaceuticals to cleaning products.

How A Simple Innovation Changes The Tablet’s Future

How A Simple Innovation Changes The Tablet’s Future

Despite being an important part to the product’s success, the shape of the tablet is given less consideration by marketing departments and are only given much attention during a campaign where the shape and color of the tablet is promoted to the public. That said, small changes in the shape can impact the public’s acceptance as well as the tablet’s efficiency.

Tablet Designs – Should you stop making round tablets?

Tablet Designs – Should you stop making round tablets?

The design of tablets requires careful research and understanding especially with respect to the shape of the tablets. Even tiny variations can have a direct impact not only on the cost of production but also on patient’s acceptance, which can lead to either the success or failure of the product.
Risk Of Mix Up And Cross Contamination

Risk Of Mix Up And Cross Contamination

A Mix–Up may be defined as:

  • An unplanned combination of various compounds.
  • A mistake brought about wrongly identifying one material for another.

A mix-up can be caused by bad judgement or lack of attention to detail, i.e., human error. It can also occur though poor communication between personnel.

The Right Capsules Are Important

The Right Capsules Are Important

The rules have changed when it comes to development of products in the pharmaceutical, health and nutritional industry. As generic and branded companies in the industry struggle with new products while at the same time addressing the need of new patients, the companies must also meet the growing productivity demands in the manufacturing industry.

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Rapid Mix Granulator – Operation and Cleaning Guide

Rapid Mix Granulator – Operation and Cleaning Guide

A rapid mix granulator is a multi-purpose mixer/processor equally suitable for high speed dispersion of dry powders (including effervescent powders) and their granulation with aqueous or organic solvents. The equipment is designed to achieve rapid mixing and the formation of consistent granules required for the production of high quality pharmaceutical tablets for solid dosage forms of medication. Good mixing and control of granule size leads to fast tableting speeds and high quality products with low rejection rate.

Production – Standard Operating Procedures

Production – Standard Operating Procedures

A standard operating procedure (SOP) is a written instruction describing how a routine task is to be carried out; when, where and by whom. SOPs play a fundamental role in continuous quality assurance and ensuring best practice for your company, in order to assist you in protecting the safety of your patients and members of the public. The implementation of SOPs, which are specific to your production facility, will help you to:

How To Protect Light Sensitive Products

How To Protect Light Sensitive Products

It is crucial that pharmaceutical companies protect their light sensitive products from direct sunlight or certain spectrums of artificial light. One way to protect it is to use brown colored light especially during manufacturing.

Process For Gowning – Entry And Exit Change Rooms

Process For Gowning – Entry And Exit Change Rooms

To prevent any contamination to the processing area or inside the building, it is important to learn the procedure for changing clothes during entry and exit through the company’s changing areas.

Color-coding can identify the personnel and their department. Color-coding for the first change room and primary change room is as indicated below:

Procedures To Follow During In Process, Off-line and On-line Packing

Procedures To Follow During In Process, Off-line and On-line Packing

In this short article we state the guidelines to follow during the online and offline packing for pharmaceutical companies.

Procedure for Moving Desktop Tablet Presses

Procedure for Moving Desktop Tablet Presses

1) Ensure that anyone moving the press is wearing the correct protective clothing. This may include:

  • Steel toe boots
  • Heavy duty grip gloves
  • Back support belt
Preventing Cross Contamination In Pharmaceutical Production Process

Preventing Cross Contamination In Pharmaceutical Production Process

There are several ways to prevent cross contamination during production and below are some ways to do so. Before starting, line clearance should be performed as per the SOP of the company. Do a checklist and record. Check to see if any starting materials are missing, previous record documents, product residues and product itself. Practice a closed system when handling the materials.

Different Preservatives And Concentration Dosage For Pharmaceutical Liquid Preparation

Different Preservatives And Concentration Dosage For Pharmaceutical Liquid Preparation

With a bigger move towards clean label LFA is seeing less and less use of chemicals in its customers products. Sometimes though it is impossible not to have to use a preservative when undertaking wet granulation.

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