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Tablet Binding

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15 April 2016 No comments

Description: The term “Binding” is used when the tablet sticks to, takes hold or splits during the molding / pressing process.

During the process, a film is built on the molding or die area restraining the ejection of the tablet. If there is excessive binding, the sides of the tablet might cracked or crumble.

If you are having consistent problems with a tablet mix sticking to dies, we recommend trying LFA's all-in-one pill mix Firmapress.

Cause: Binding usually occurs when there is little or lack of lubrication, too much moisture in the granules used and using worn out or old dies.

Binding issues caused by the granulation process

ProblemSolution
Moist granules. Moisture can be seen around lower punch.Increase drying time of granules
Noisey ejection (ocassional cracking tablets)Increase the quantity of lubricant used
Overly Coarse GranulesReduce granular size by adjusting mesh size on granulation machinery
Excesively hard granules. Too hard for the lubricant to be effectiveRedue mesh size of granule. If using wet granultion process, reduce drying time.
Granular material brassive and damaging toolingReduce size and density of granules. If not possible then use higher density tooling
Granular material sticks to dieIf too warm reduce tempreture. Increase clearance if it is extruding

Binding issues caused by the machinery or tooling

ProblemSolution
Bad quality toolingPolish to improve finish or purchase new tooling
Rough die surfaces due to abrasionReplace tooling with higher quality tooling
Undersized dies. Too little clearaceMachine down dies to increae clearance
Too much pressureReduce pressure or modify granulation