Silicon Dioxide

Only %1 left
  • Anti-caking Agent
  • White Powder
  • High Grade Silica
Prefer to pay by Invoice? Request Quote

Connect with Our Team

If you have a question, require bulk pricing or would like more details about Silicon Dioxide, please complete the form below and someone from our team will be in touch with you soon.

Silicon dioxide, also known as silica, is used in tabletting to increase manufacturing efficiency. It is an inert ingredient, meaning that it won’t react with other ingredients or substances in the body. It has a high melting and boiling point, and it is insoluble in water. There are natural and synthetic grades of Silicon Dioxide, but each have an identical chemical make-up. It is a popular excipient ingredient as it increases flowability and stops caking on tooling, and also eases digestion.

With a high porosity that allows it to absorb up to 300 g of fluid per 100 g of silica, Silicon Dioxide efficiently absorbs moisture from its surroundings. It enables liquid ingredients to turn into free-flowing powders, making it a popular choice for the pharmaceutical, cosmetic and food industries. It also acts as a glidant, a substance used in a formula to improve its flow qualities, ensuring that the product flows quickly through machinery and doesn’t stick to the equipment. It reduces traces of moisture which may otherwise cause your machinery to degrade.

With its unique moisture absorption properties, Silicon Dioxide will encourage quick tabletting due to its resistance to capping and sticking, and also increase the stability of moisture-sensitive Active Pharmaceutical Ingredients, or APIs. The different benefits work together to create an easier, smoother and more efficient manufacturing process.

Silicon Dioxide, also known as quartz, is an interesting element that is abundant on this earth. It makes up 60% of the Earth’s crust and 93% of known rocks. It is found in plants, in our food and our body tissues, and is necessary for healthy bones, skin, hair, teeth and nails. Silicon Dioxide deficiency can result in poor bone formation, unhealthy skin and teeth.

It is important to handle Silicon dioxide correctly to keep people safe and to increase the product's shelf life. It can irritate eyes and skin if they are exposed to it. Avoid inhalation and wear a mask whilst handling it. If the product is handled properly, it will stay in excellent condition until it’s ready for use.

Name Value
CAS Number 7631-86-9
Molecular formula 60.08 g/mol
Appearance White powder
Physical state Solid
Storage Store at room temperature
Melting point 1,713 °C
Density 2.648 (α-quartz)
2.196 (amorphous) g·cm−3
Bulk Density 0.05g/cm3
Molecular weight 60.08 g/mol
Documents Intolerance Data
Technical Specification
Write Your Own Review
You're reviewing:Silicon Dioxide
Your Rating
Are all excipients safe for all ages to consume?

Yes, it does not matter what age, size or sex the person consuming the products is. It is, however, important to check the intolerance data.

Are all the excipients safe for human consumption?

Yes, all of the excipients are safe for human or animal consumption. There are some precautions that should be taken when handling them and there are some people that might have intolerances to some of them. Information on this can be found in the products MSDS and Intolerance Data Sheet. This can be found in this section for every excipient.

Are there any known allergens or health risks?

Yes, there are all of them can be found in the intolerance sheets for each product. The intolerance sheets can be found here:


Can I get a better price for excipients than is listed on the website?

Yes, we have bulk pricing for all of our excipients, and these can be found in this section. We offer bulk in 500 kg, 1 ton, 2 ton and 5 ton lots. The prices are set on these quantities as these are the amounts that will fit on pallets.

Can I have a CoA for my Excipient?

Yes. CoA stands for Certificate of Analysis this is also known some times as an MSDS (Material Safety Data Sheet) all of the information contained in a CoA is inside the MSDS for every LFA product which is emailed to you after purchase.

Dissolving rate? Any known factors that can affect the rate, speed up or slow down the breakdown of a tablet?

Yes. There are two things at play here. You can get hygroscopic and hydrophobic excipients. Hygroscopic means that they take on water quickly, while hydrophobic means that they repel water.

There are products know as supper disintegrants. These products help the breakdown of tablets. At the moment LFA does not sell any supper disintegrants.

Magnesium stearate is hydrophobic this means that it will slow the breakdown of a tablet.

However, it is used in such small amounts that most of the time it will not make a difference to our customer's products. If they would like to be sure then they should conduct what is known as a disintegration test.

How long is the storage period of each excipient? What is the shelf life?

Firmapress - 2 years form batch date.
Dextrose - 3 years from batch date.
Dicalcium Phosphate - 3 years from batch date.
Microcrystalline Cellulose -
Magnesium stearate -
Lactose - 2 years from batch date.
Silica Dioxide - 2 years from batch date.

How should I clean contact parts that have come into contact with my excipients or active ingredients?

here are 6 steps that should be followed as a general rule of thumb when cleaning contact surfaces that have come into contact with powders:

Dry Clean - First you need to remove as much of the dry powder as possible. You can do this using a hover/vacuum. Make sure that the vacuum you are using has a filter good enough to handle fine dust.

Wet Clean - Next you need to perform a wet clean. This can be done with warm water and soap or if available an ultrasonic cleaner.

Rinse - Next you need to rinse off any soap with potable water (drinking water). You do not have to do this if you used an ultrasonic cleaner in the last step. It is important to ensure that all parts are thoroughly dried immediately after washing to avoid any rusting.

Sanitise - Next you need to sanitise the surface. This step is recommended by the FDA. There are a number of sanitising solutions available designed to be applied and left on.

Lubricate - You now need to lubricate any parts that require it. This should be with the appropriate grade oil or grease considering your use and greasing chart. Store - Finally store any of the parts in a cool dry place. If you are storing them on the machine then make sure the machine is in a temperature controlled environment with low humidity.

What is the mesh size of your excipients? etc.

Dextrose - approx 100 mesh
Dicalcium Phosphate - approx 100 mesh
Microcrystoline Cellulose - approx 120-200
Magnesium sterate -
Lactose - 80 mesh
Silica Dioxide -
Firmapress - 100-200 mesh

What kind of agent is each excipient?/ What is the main use of each excipient?

Dextrose - Sweetener, binding agent, good for chewable tablets or candy.

Microcrystalline Cellulose - Binder, filling agent. Good at binding tablets and making them bigger. It can also be used as a filler for capsules.

Magnesium stearate - Dry Lubricant. This stops products from getting stuck to the tooling. It can also help with powder flow issues and caking issues.

Lactose - Binder, sweetener and bulking agent. It has a large mesh so it flows well but most people do not like it because of the intolerance issues.

Silica Dioxide - Flowing agent. This assist powders in flowing smoothly through the machines. It also helps with cacking issues where powders get stuck to the machine.

What kind of condition should excipients be stored in?

Firmapress - 2 years form batch date.
Dextrose - 3 years from batch date.
Dicalcium Phosphate - 3 years from batch date.
Microcrystalline Cellulose -
Magnesium stearate -
Lactose - 2 years from batch date.
Silica Dioxide - 2 years from batch date.

Which excipient should I add if the product doesn't bind well?

If your product does not bind well then we would recommend using MCC. This can be used in any % the limiting factor is the size of the tablet.

If the amount of MCC you would have to use would be too much or if you do not want to use MCC then you have 3 other options: Ask your supplier for a directly compressible or tabletable grade of your product. Spray dry your product. Wet granulate your product.

Which excipient should I add if the product is sticky?

If your product is sticky then you will need to add a dry lubricant to your mix. For this, we recommend magnesium stearate.

We do not recommend that you add more than 1% to the mix as more than this can cause capping. If your product is still sticky at this point then we would recommend looking into granulation.

Which excipient should I add if the product/API is clumpy?

If your product or API is clumpy then you will need to add an anticaking agent. For this, we recommend silicon dioxide. We only recommend adding a maximum of 2% of this to the mix

Frequently Bought Together
  1. Magnesium Stearate
    Magnesium Stearate
  2. Microcrystalline Cellulose
    Microcrystalline Cellulose
  3. Sorbitol, DC
    Sorbitol, DC
  4. Dextrose, DC
    Dextrose, DC
© 2024 LFA Machines Oxford LTD. All Rights Reserved.