How to make a Tablet Pill mix for a Press 5
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Okay so we're back at the able now and 'm going to weigh up my ingredients as I calculated them to be. The first one I calculated was my binding and coloring agents, and I calculated that I need 53.3 of that in my mix to be able to make my hundred gram sugar tablets. We'll just scoop this up. Get it all on the spoon, get it in there, don't waste a bit. 53.3, I've slightly over, 54, 53.9, 53.7, there we go, 53.3, and then on top of that, I'm going to add my 10 grams of brown sugar as I calculated it so I'm now going to take the mix up to 63.3, and there it is. Next we are going to mix it all up. You can purchase mixers here, and they are definitely a very, very, very worthwhile investment. If you're working with something very crystalline and it's in big chunks, then the best thing to do would be to use a mortar and pestle to reduce it down to smaller granules like sugar, or if you don't have access to a mortar and pestle or if you're going to be doing it on a very large scale, then I am also able to get a hold of granulators. If you just go to the "contact us" section of our webpage and let us know what you require, we will get back to you as soon as possible. Now that that's all mixed up we will move back over to the press, and we will tablet up these 100 tablets.
Okay so we're back at the press and we've got our active ingredient that's been mixed really, really, thoroughly now with our binding agent, and we're going to spoon feed this into there. Well, try not to get it everywhere, but it's only brown sugar. The first thing that we're going to do, which you should really get into good working practice, which is a very good working practice thing to do, is we are going to crank the first tablet out by hand. That just ensures that our new tablet mix, our new active ingredient, it's going to work, it's not going to damage our machine. So here we go, we are putting out the first tablet by hand, and yep, it clicks over and yep, it comes out, and yes, we have one brown, speckled, brown sugar vitamin tablet. We're now going to put on the machine and do a run, and hopefully minus the powder that I just stupidly dropped on the floor, we should get as near to 100 tablets as is possible.
We're going to count them up, and we're going to see how close we got. As you can see just here there is a little bit of over spill. What I tend to do is I tend to set up a tinfoil tray right on the base of the TDP 5 tablet press. I calculate that spill to be between 5% and 10%. If you are doing a big run obviously, use a painters brush, a dry paint brush, to scoop it onto the tinfoil around the base of your press, and then just pop it back in on the shoot, and then you can reduce your loss down to about 1% maybe half a percent on a really big run so you're really not losing a lot. It's not a lot to be worried about.
We're back at the table, and I've lined them up into rows of ten, except for this ten, which you can see is four short so we got 96 tablets out of our mix that was meant to create 100, which is fantastic. I'm pretty happy with that kind of accuracy. It's just 4% out. And as you saw when I was filling the machine, I did actually spill a little bit so I'm not too disappointed in that at all. And if I pop on the scales, hopefully, and take any one of these random tablets it should weigh about 0.6. 0.7, but these are only single digit scales. If we put ten on there, ten random ones, what are we going to get? Hopefully we're going to get about 6 grams, which would work out perfect. Well I suppose this is going to work out slightly more because it is 0.63 per tablet, but 2, 4, 6, 8, 10, and there it is.
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