Drugs are substances specifically recognised by an official Pharmacopeia and Formulary and approved for use to treat, diagnose, cure and prevent a disease or disorder. A substance induces change to the function and structure of the patient’s body.
Pet owners can relate when it comes to the problem of giving medicine to one’s pet which can be a tough battle. As most capsules or pills have synthetic smell to it the tendency of the pet would be to refuse to swallow it. Some pets can be stubborn even running away once they see you coming.
Although one can encapsulate liquids in a gelatin or vegetarian capsule, the truth is that the process of encapsulating is both a science and an art. The product usually depends on the weight and quality of the formulation as well as other variables that can affect it.
The steam jacketed kettle or evaporating pan is an example of natural circulation evaporators. It is made up of a hemispherical shape with large surface area for the evaporation. The pan can be permanent and emptying is done through the outlet. The pan is mounted in a way that they can be tilted to take out the product. The pans are heated by the steam that comes out of the steam jacket.
Calcium is a mineral that is an important component of the human diet for building strong bones and teeth, and also for regulating certain body processes.
A single stage process, which results in quicker production. Minimal weight gain of tablets is at 2 – 3% compared with sugar coating which adds 60 to 80%. The film coat will not likely affect the tablet’s disintegration process.
One benefit of film coating is that it is easy to automate making it easier to comply with GMP requirements for Standard Operating Policy. It holds the ability to maintain its shape and allows for embossing.
The coating process plays a crucial role in tablet coating and many of the issues or problems arising come from the process setup. The different variables that affect the film coating should be addressed and how these variables play a crucial role in the coating process. The equipment type for film coating is also tackled in the article.
Vitamin D is necessary for maintaining good health, but 40 to 75% of the world's population is deficient. The vitamin is not found in many foods. Fortified milk, eggs, fish and beef liver are some of the few containing vitamin D and even in these the amounts may be small.
The Fluidized bed dryer is common in the pharmaceutical industry and widely used during the granulation process where granules undergo the drying process. The dryer allows the manufacturer to obtain the desired moisture content for the tablet formulation.
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Drying in the pharmaceutical industry involves the extraction of liquid and other liquid solvents from the materials or granules using air current or heat. Fluidized bed dryer is one of the equipment used to dry the granule particles using the FBD finger bag.
When people first think of tablet or pill presses they think pharmaceuticals, supplements, vitamins and minerals or just medicines. But tablet making machines can be used for other purposes.
The principles of GMP are a follows, the structure, device and equipment should be designed, installed, placed, operated and maintained as per its intended use and purpose. Integral system whose consistency in performance and having an impact to product quality should be validated whenever appropriate such as the air handling system, water purification, compressed air system and stem system.
This article covers general GMP procedures. Including QA staff must do a round of the plant area making sure that the plant adheres to the cGMP and fill up the checklist provided by the company. Head or In-charge personnel should review the plant audit and discuss this with the person in charge of the plant after which the audit report will be closed.
The packing process is an integral part of the manufacturing process for pharmaceutical products. Below is a summary of good practices that may help streamline the packing process.
The multi tooling equipment has long been used in the pharmaceutical industry and has been in existence for more than 150 years. During the start of the tablet compression industry, companies use single station presses during production and these were outfitted with
As our world becomes more connected and information is shared quite easily in the internet today, people are more curious about where their food comes from. One question that begs to be answered is where gelatin capsules are made of and this is an interesting especially for individuals who pay attention to what they eat. Gelatin capsules are made of natural ingredients and below are some interesting things on how the capsules are manufactured.
If you have never changed a die or you need to refresh your knowledge, this How-To will tell you to step by step how to change your TDP die.
There is a diagram of a desktop press at the bottom to help you identify the location of the parts you will need to remove during this process.
Before shipping, it is imperative that the vendor does a proper Factory Acceptance Test or FAT in order to prevent any problems during the product installation. Below is a sample of what should be indicated in the FAT protocol.