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Common Tablet Problems And Solutions

Common Tablet Problems And Solutions

There are varieties of problems that face the pharmaceutical world, some of which we will be discussing as well as solutions that would help solve these problems.

  • Overwetting of the tablets/Surface pitting. This is where suspension droplets hit the still wet tablet and the drying air does not dry it enough.
  • Physical damages overloading or unloading operation.
  • Poor tablet design – flat surfaces.
  • Spray Drying. The suspension droplets hit the tablet after the moisture has been removed. This leads to the poor adherence of the coat
Compression Tooling Equipment

Compression Tooling Equipment

Changing the tablet manufacturing process can lead to better and more improved quality products as well as cost efficiency for the company. By communicating with one’s tooling vendor and taking into consideration the right material type, one can overcome the many problems that tablet companies are facing today.

Contaminants Caused By Humans And Methods Of Control

Contaminants Caused By Humans And Methods Of Control

One of the major problems with sterile manufacturing is the possibility of contamination. The cleanroom area is one of the hardest places to maintain sterile or clean and is the major source of contamination.

Different Types Of Contamination, Causes And Prevention For Pharmaceutical Industry

Different Types Of Contamination, Causes And Prevention For Pharmaceutical Industry

The presence of unwanted materials such as dust and particles during the manufacturing and transportation time is called contamination. The term contaminants includes any unwanted matter that is found in the product. These contaminants affect the quality of the product or the process.

Dial with segments from green to red symbol of risk control or limit

Cool Chain Drugs | What are Cool Chain Drugs?

In the pharmaceutical world, there are certain medicine products that needs certain specific temperature in order to maintain its efficiency, structure and safety.

Healthy everyday nutritional supplement, Vitamin pills and herbal capsules in the bottles

CoQ10 - Why It Should Be Part Of Your Range

Coenzyme Q10, often called CoQ10, is a compound that occurs naturally in the human body. All the cells of the body produce this enzyme, which helps to produce energy for normal cell maintenance and growth.

Cup Depth Demonstrated On Tablet Press Tooling

​Cup and Tablet - Depth and Consistency

The cup depth is the space between the punch tip and the lowest possible measurable area of a cup cavity. In order to form proper inspection and wear limits of the tooling equipment, it is important that one should know about it, and how premature wear can affect the tablet.

Is A Vegetarian Capsule Much Better than One Made of Gelatin

Is A Vegetarian Capsule Much Better than One Made of Gelatin

Medicines are a go to whenever one experiences health problems. From over the counter medicines to prescriptions, these pills have become vital to our everyday lives. Due to the advancement in technology, two different forms are now available – tablets and capsules. For some time, tablets are quite popular way of taking in medication or supplements; later on however, consumers discover the effects of taking tablets.

What is the difference between the TDP 1.5, TDP 5 and the TDP 6s?

What is the difference between the TDP 1.5, TDP 5 and the TDP 6s?

This is a frequently asked question on the TDP range. This range of single station pill press includes the TDP 1.5, TDP 5 and TDP 6s. The machines are very similar and the main distinction between them is the pressure that is exerted during tablet making.

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Different Lubricants Approved For Pharmaceutical Machine Use

Different Lubricants Approved For Pharmaceutical Machine Use

The use of lubricants during manufacturing is crucial as it minimizes the friction between the different parts of the machine. Reducing friction is important as it can cause heating between parts. Adding lubricants also help reduce the tendency of parts to rust and decrease load in the machine.

Tooling Designs – Different Mixes Need Different Punches

Tooling Designs – Different Mixes Need Different Punches

It has always been difficult to market a tablet in the industry today. Aside from time and capital, research and development is also important; that said, one of the most difficult phases is the actual production of the tablet. Plenty of issues arise during production, including tablet quality to downtime of tablet equipment, which can result to delay in shipping of the product. There are steps that one can take to eliminate as well as minimize the issues before manufacturing actually begins.

Broken white tablets

Solutions For Tablet Sticking

One of the major problems that the tablet manufacturing companies faces is tablet sticking. This problem occurs when the granulation sticks to the punch surface causing deformed tablets, which is very costly not only for the manufacturers but also for the formulators. One way to alleviate this problem is using analytical method as well as create screening processes. Authorities or field experts are also looking for ways to create analytical models to identify the solutions quickly for specific problems.

Tablet Coating Defects and their Remedies

Tablet Coating Defects and their Remedies

Coating tablets with a thin polymer film can be an effective way to give your products a professional edge. High quality tablets can be quickly and easily produced using a tablet coating machine and the correct excipients . Unfortunately several defects can arise with coatings. The following list provides helpful remedies for common issues that may be encountered.

Thermocouples sensor probe isolated on white background

Different Temperature Sensors - Thermocouples, Thermistors, RTDs

Pharmaceutical companies make use of different temperature sensors due to their accuracy. Currently three sensors are widely used in the industry. Below is a brief on the three sensors.

Different Tooling Equipment For Oral Solid Dosage Tablets

Different Tooling Equipment For Oral Solid Dosage Tablets

Solid dosage forms are forms or shapes where drug mixtures are placed, example of which include tablets and capsules. These solid dosage forms are administered orally.

Tablets are defined as Solid Pharmaceutical Dosage forms that contain drug substances. They may contain suitable diluents or are prepared through moulding or compression.

Different Types Of Parenteral Preparations

Different Types Of Parenteral Preparations

Parenteral preparations are sterile pharmaceutical products administered to the human body by injection. Only liquids can be injected which means that the pharmaceutical parenteral preparation must either be a liquid which can itself be injected safely, or it may be a material that can be diluted with sterile water (commonly referred to as ‘water for injection’) or other sterile solvent before it is administered. Liquids other than water must not interfere with the stability and efficacy of the preparation. Some substances may be added to increase the stability and efficacy of the preparation, but it is important that such additives do not cause adverse effects or toxicity. Coloring agents are not permitted in parenteral preparations.

Different Ways to Administer Drugs

Although LFA Tablet Presses specializes in Pill Presses and Tableting Equipment we understand that this is not always the best method of delivery. In this article we look into the other options available to you as a business with which to package and deliver your product.

White sugar and brown sugar in a bowl

The Different Dosage Forms Manufactured In The Industry

A drug is defined as a mixture of compounds used in the pharmaceutical industry to treat and prevent diseases. The different drug forms help health care providers to administer the drug safely. In this article LFA discusses the different forms of drug dosing and how best you can use them in your business.

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