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The process of sugar coating is rare in the pharmaceutical world recently. That said, knowing the problems that one can encounter would help in the event that sugar coating is needed and problems arise.

Most tray dryers used in the pharmaceutical industry comprise a heated cabinet in which a rack of trays is located. They are frequently used for the drying of granulated powder. Heat can be provided by burning a fuel, e.g. natural gas or, more usually, by one or more electric elements located within the cabinet, together with a blower to circulate the air.

Tray dryers are devices used to dry wet products of chemicals, powders and crude drugs. The simplest way to explain a tray dryer is a cabinet that has a heater at the bottom or a laboratory oven. The oven has little to no value because control is non-existent for humidity and heat transferred.

Tablets are defined as solid form of drug dosages where each unit is made up of one or more medicaments. Administered orally, the tablets are made up of powdered drugs with excipients that are compressed into its solid form.

Tablet Coating machines are equipment devices used to coat the tablet’s outer surface with a thin coating film.

Tablet packaging machines comes in different types and is categorized as follows

Tablet machines, also called as compressing machines or tablet presses, are the equipment used to compress the powder into its tablet form forming uniform size, shape and weight.

Description: Double Impression includes punches that embed monograms or images on tablets.

Cause: During the impression stage, each tablet undergoes imprinting. In the said stage, engraving machines imprint on the tablet; with the double imprinting, the lower punch might be uncontrolled and drops freely the short distance causing a new imprint on the tablet producing the double imprint on the tablet.

There are two principal methods of coating tablet: sugar coating and film coating. Both have advantages and disadvantages, and the following table provides a comparison between the two methods. The choice of which method is appropriate depends to an extent on how the tablets have been produced, the composition of the tablet and the intended market.

The dry granulation process is a process whereby granules are formed without the aid of any liquid solution, as the ingredient to be granulated is moisture- or heat-sensitive. To form these granules, it is important to use compacting and to densify the powder. A slugging tool or a roller compactor tablet press machine is used to conduct the dry granulation process.

Validation is establishing documented evidence which provides a high degree of assurances that a specific process or equipment will consistently produce a product or result meeting its predetermined specifications and quality attributes.This article focuses on the process of dry mixing of powders, as one of the steps in producing tablets.Validation can therefore be applied to the dry mixing process itself, as well as the overall manufacture of tablets.

Capsules are the preferred way for many people in taking their medications or even vitamin supplements. Not only does it dissolve quickly, it is also easy to fill for both commercial and home consumption. When it comes to having it compared with other ways of taking drugs, the capsules are not affected by the formulation inside it and thus do not affect the drug effectivity.

In sterile pharmaceutical preparations such as required for injectable dosage forms, the drugs are often supplied in glass vials. These should be cleaned before filling, and although automatic vial washing machines may be used to clean vials, it is important to have the cleaning process validated. The efficiency of the washing machine and process is verified by performing several tests, as follows.

The manufacturing of a tablet includes compressing a drug with several excipients. Mere compaction of a dry powder between two punches yields a tablet that easily crumbles.

In wet granulation, powders are bound together using adhesives rather than compacting motion. As more liquid is added to the mix, bridges form between the particles, which increase the tensile strength of bonds.

The process of wet granulation includes the massing of mix dry powders with granulating fluid. The fluid contains solvent, which can easily be removed when dried. The fluid should be non-toxic and may include water, isopropanol, ethanol and methylene; they can be used alone or combined with other solvents.

The oral liquids are homogenous liquid preparations, which contain an emulsion, solution and suspension of one or more active ingredients that are suitable as liquid base. These preparations are administered either as is or after dilution. The preparations contain other substances such as emulsifying, dispersing, solubilizing, stabilizing, suspending, wetting, thickening agents and antimicrobial properties for preservation.

What Is The Right Compression Tooling Equipment To Use

Tablet manufacturers need to choose the right compression tools to ensure that high quality tablets are produced. Before equipment is purchased therefore, it is important to establish good communication between manufacturer and equipment supplier.

The industry has been undergoing revolution lately with the increase in the number of patents expiring and the growth of generic producers as well as increase in contract manufacturers. Another force is the increase in the competition with developing markets and other companies that are relocating their facilities to take advantage of these.