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4 Major Health Benefits of L-Lysine

4 Major Health Benefits of L-Lysine

If you're a fan of the movie Jurassic Park, you may remember something called ‘the lysine contingency,’ which ensured that the dinosaurs couldn't live for long outside the park. The dinosaurs were genetically altered so that they needed L-lysine supplements in order to survive.

Well, guess what - humans need L-lysine, too!

5 Benefits of Creatine Supplements

5 Benefits of Creatine Supplements

If you've been in the health supplement industry for a while, you've probably heard of creatine before. It's a common fitness supplement that is sold over the counter at sports and fitness stores across the world. But do you really know all of the great benefits that creatine offers you? Read on if you're curious about how creatine can benefit your customers health.

Aloe Vera's Weight Loss Benefits

Aloe Vera's Weight Loss Benefits

Recent research on the effects of aloe vera on weight, body fat mass and fasting blood glucose indicates that there may be a connection between the plant and weight loss.

An Overview of Disintegrants

An Overview of Disintegrants

药品活性成分被人体吸收的能力取决于它的生物利用率。而生物利用度取决于药品通过肠道时,活性成分在消化液中的溶解程度。而溶解程度取决于药品的物理形态和化学成分。药片的崩解能力关系到它在体液内的溶解程度。对于大多数片剂而言,需要打破压片过程所致的颗粒凝聚力才能有效崩解。在压片之前,某些片剂产品为了将粉料结合而加入粘合剂,那么它们的崩解过程将比较困难。还有一些片剂的活性成分包裹在不能崩解的外壳内,以防止活性成分接触胃液,让药片溶解的过程难上加难。为确保片剂在人体内的分解速度足够快,每制作一批片剂前,都需要对配方进行一次例行测试。 

崩散剂片剂配方胶囊中的一种赋形剂。它提升片剂或胶囊接触液体时的崩解能力。多年来广泛应用的崩散剂有多种,它们的作用机制各不相同:(a)提升毛血管作用力,从而加强吸水能力(b)遇水后膨胀促进药片崩解(c)释放气体直接加快片剂的崩解。在产品配方中加入一种或多种崩散剂是为了提升产品的表面积,减弱固体微粒之间的凝聚力。这样起到的效果是,当片剂接触水媒介时,先崩解成颗粒,然后崩解成微粒。如图所示,片剂或胶囊在水媒介中的溶解率随着颗粒变小而上升,当片剂或胶囊崩解成微粒时,溶解率达到最高。1.快速溶解提升活性成分在人体内的吸收率,从而得到期望的治疗效果。需注意,咀嚼式的片剂产品不需要再配方中加入崩解剂。

Close up shot of different types of capsules

An Overview of Encapsulating Liquids

Although one can encapsulate liquids in a gelatin or vegetarian capsule, the truth is that the process of encapsulating is both a science and an art. The product usually depends on the weight and quality of the formulation as well as other variables that can affect it.

An Overview Of The Fluidized Bed Dryer

An Overview Of The Fluidized Bed Dryer

The Fluidized bed dryer is common in the pharmaceutical industry and widely used during the granulation process where granules undergo the drying process. The dryer allows the manufacturer to obtain the desired moisture content for the tablet formulation.

An Overview of Vegetarian Capsules

An Overview of Vegetarian Capsules

The advancement in science and technology makes it easier for one to make their own supplements. Vegetarian capsules are healthier as these are derived from natural ingredients such as cellulose, hydroxyl and methyl. If you are looking for a healthy and natural alternative to traditional capsules, then vegetarian capsules can be an excellent choice for you.

Benefits of Enteric Coated Capsules

Benefits of Enteric Coated Capsules

Whether a capsule is made of gelatin or vegetarian ingredients, it is intended to dissolve in the stomach. However, there are times when it benefits the person to have the capsule dissolve in the small intestine and this is what enteric-coated capsules are created for.

Benefits of Whey Protein Powder Supplements

Benefits of Whey Protein Powder Supplements

Whey protein is the highest quality protein source. Many types of whey protein powder supplements are available in stores. The demand is very high however, due to the many benefits associated with consuming whey protein powder.

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Best Bodybuilding Supplements For Women

Best Bodybuilding Supplements For Women

Bodybuilding is a sport that most people think is for men only. But it is also a sport for women and is rapidly growing in popularity. When women become bodybuilders, they usually don't have the same goals as men. Often, they want to become a certain size, build strength and confidence and then build muscle.

Binder Types and Properties Used in Tablet Manufacturing

Binder Types and Properties Used in Tablet Manufacturing

Binders are chemical compounds that have an adhesive property. They bind the drug and excipient together and provide it with extra strength. Binders can also form intergranular bonds that fuse together and form a binder bridge between granules adhering to each other. The bridges may result from the melting or softening of the binder during the compression process.

Breaker Lines - Good or Bad?

Breaker Lines - Good or Bad?

The use of scoring on tablets has long been implemented by the manufacturing industry mainly to prevent stress fractures but later on for more considerations that are primarily aesthetic. Bisects are different as they present a challenge to manufacturers as they can affect the tablets.

Building strength in to your design

Building strength in to your design

The tablet land is a slight level surface that is vertical to the tablet’s boundary creating a junction between the boundary and the cup of the tablet. There are three main reasons why one would incorporate a land into the tablet’s design.

  1. Increase the strength of the punch edge
  2. Increase the wear of the punch cup inner edges
  3. Lower the relentlessness of the nicks on the edges of the punch
Capsule Dosage Forms – Hard Gelatin, Soft Gelatin, Modified Release and Enteric

Capsule Dosage Forms – Hard Gelatin, Soft Gelatin, Modified Release and Enteric

Although LFA Tablet Presses does not sell capsules or capsule fillers we do feel that it is very important to provide our customers with as much information as possible. In this article we discuss the types of capsules and the their potential applications.

Case Studies in Capsule Filling – Improving Performance, Effectiveness and Productivity

Case Studies in Capsule Filling

The rules have changed when it comes to development of products in the pharmaceutical, health and nutritional industry.

Checking Your Tooling

Checking Your Tooling

It is time consuming and expensive for tablet manufacturers to inspect tooling equipment. That said, changes and advancement in technology makes it easier to doin-processinspections. Below is a brief on the improvement in technology to improvein-processinspection.

Cleaning Agent Used For Pharmaceutical Companies

Cleaning Agent Used For Pharmaceutical Companies

The nonionic detergents are the type of cleaning agent used in the pharmaceutical industry as it helps sanitize and protect the equipment in order to prevent poor quality and thus uphold the quality of the product.

Common Problems in Tablet Compression

Common Problems in Tablet Compression

In the tablet manufacturing industry, the most common problem that they encounter is what one would call as “Sticking”. This happens when the granulation sticks to the tool face, which results to sticky products and failure of the presses to compress the tablets. This is a big problem for manufacturers as the sticking goes unnoticed and only seen once the item is in production.

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