The dry granulation process is a process whereby granules are formed without the aid of any liquid solution, as the ingredient to be granulated is moisture- or heat-sensitive. To form these granules, it is important to use compacting and to densify the powder. A slugging tool or a roller compactor tablet press machine is used to conduct the dry granulation process.
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Validation of dry mixing and tablet production processing
Validation is establishing documented evidence which provides a high degree of assurances that a specific process or equipment will consistently produce a product or result meeting its predetermined specifications and quality attributes.This article focuses on the process of dry mixing of powders, as one of the steps in producing tablets.Validation can therefore be applied to the dry mixing process itself, as well as the overall manufacture of tablets.
Understanding Tablet Coating Process
There are two principal methods of coating tablet: sugar coating and film coating. Both have advantages and disadvantages, and the following table provides a comparison between the two methods. The choice of which method is appropriate depends to an extent on how the tablets have been produced, the composition of the tablet and the intended market.
Understanding Double Impressions On Tablets
Description: Double Impression includes punches that embed monograms or images on tablets.
Cause: During the impression stage, each tablet undergoes imprinting. In the said stage, engraving machines imprint on the tablet; with the double imprinting, the lower punch might be uncontrolled and drops freely the short distance causing a new imprint on the tablet producing the double imprint on the tablet.
The Different Types Of Tablet Press
压片机,也称为粉末压片机或粉末成型机,是将药粉压制成片剂,生产大小、外形及重量相同的片剂的机器。压片机还可以用于制造其他片状的产品,例如化妆品、清洁产品以及石油化学工业的催化剂。
The Different Types of Tablet Packing Machines
Tablet packaging machines comes in different types and is categorized as follows
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Types of Tablets
Tablets are defined as solid form of drug dosages where each unit is made up of one or more medicaments. Administered orally, the tablets are made up of powdered drugs with excipients that are compressed into its solid form.
Tray dryers for drying wet, sticky or granulated products
食品干燥有多种技术,包括托盘式烘箱、隧道式烘箱、喷雾干燥机、滚筒干燥机和冻干机等。托盘式烘箱非常适合用于干燥湿润的化学品、粉末及原料药。
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Tray Dryer – Operation And Cleaning Guide
Most tray dryers used in the pharmaceutical industry comprise a heated cabinet in which a rack of trays is located. They are frequently used for the drying of granulated powder. Heat can be provided by burning a fuel, e.g. natural gas or, more usually, by one or more electric elements located within the cabinet, together with a blower to circulate the air.
The Pigeon Problem - How to make organic tablets
在过去7年的时间里,LFA看到了压片机的各种用途。现在,当有人问我们如何压制玻璃、金属、甚至咖啡粉时,我们一点也不会感到惊讶。不过,某次“鸽子”的问题我们第一次听到。
The Process Of Sugar Coating And Problems That One Can Encounter
The process of sugar coating is rare in the pharmaceutical world recently. That said, knowing the problems that one can encounter would help in the event that sugar coating is needed and problems arise.
The Mechanism Of Granulation - Formation And Methods
Granulation is the process whereby powder forms are bound together to form aggregates, which are called as granules. Granulation is important as it helps prevent the separation of the ingredients in the mixture as well as improves the flow of the properties of the mixture. It also changes the size of the particles resulting to improved compression and density of the powder mix.
What is the best type of dehumidifier to use when manufacturing tablets?
Even the simplest form of pharmaceutical manufacturing process can involve a range of process steps before the product is packaged and shipped to the consumer.These may include:
Humidity – how much is required for tablet making?
Poor environmental control, particularly in terms of air humidity can directly affect the pharmaceutical production line in a number of ways. Levels of humidity below 45%RH will allow electrostatic charges to build up in machinery and materials.
Tablet Making Definitions
Here is a list of commonly used terms and there definitions. This it to help you understand and navigate our website more easily. We hope you find it useful.
If there is something that you feel needs adding to the list then please feel free to get in contact and we will add it.
Tablet Deduster Machine – Operation And Cleaning Guide
The following is a brief operating and cleaning guide that can be used for most tablet de-dusting machines. It covers pre-start up, operation and cleaning, and lists some precautions that can be taken to help avoid contamination issues.