Articles Granulation

The use of lubricants during manufacturing is crucial as it minimizes the friction between the different parts of the machine. Reducing friction is important as it can cause heating between parts. Adding lubricants also help reduce the tendency of parts to rust and decrease load in the machine.

With a bigger move towards clean label LFA is seeing less and less use of chemicals in its customers products. Sometimes though it is impossible not to have to use a preservative when undertaking wet granulation.

Pharmaceutical companies make use of different temperature sensors due to their accuracy. Currently three sensors are widely used in the industry. Below is a brief on the three sensors.

Solid dosage forms are forms or shapes where drug mixtures are placed, example of which include tablets and capsules. These solid dosage forms are administered orally.

Tablets are defined as Solid Pharmaceutical Dosage forms that contain drug substances. They may contain suitable diluents or are prepared through moulding or compression.

The presence of unwanted materials such as dust and particles during the manufacturing and transportation time is called contamination. The term contaminants includes any unwanted matter that is found in the product. These contaminants affect the quality of the product or the process.

Parenteral preparations are sterile pharmaceutical products administered to the human body by injection. Only liquids can be injected which means that the pharmaceutical parenteral preparation must either be a liquid which can itself be injected safely, or it may be a material that can be diluted with sterile water (commonly referred to as ‘water for injection’) or other sterile solvent before it is administered. Liquids other than water must not interfere with the stability and efficacy of the preparation. Some substances may be added to increase the stability and efficacy of the preparation, but it is important that such additives do not cause adverse effects or toxicity. Coloring agents are not permitted in parenteral preparations.

Although LFA Tablet Presses specializes in Pill Presses and Tableting Equipment we understand that this is not always the best method of delivery. In this article we look into the other options available to you as a business with which to package and deliver your product.

In the pharmaceutical industry, sieves and screens are commonly used in determining the size of the raw materials. The most common way to measure the sieves and screens is by meshes. On the average, about 40 to 400 sieves are used in the industry especially during the milling and sifting of the raw materials.

Pet owners can relate when it comes to the problem of giving medicine to one’s pet which can be a tough battle. As most capsules or pills have synthetic smell to it the tendency of the pet would be to refuse to swallow it. Some pets can be stubborn even running away once they see you coming.

The steam jacketed kettle or evaporating pan is an example of natural circulation evaporators. It is made up of a hemispherical shape with large surface area for the evaporation. The pan can be permanent and emptying is done through the outlet. The pan is mounted in a way that they can be tilted to take out the product. The pans are heated by the steam that comes out of the steam jacket.

Calcium is a mineral that is an important component of the human diet for building strong bones and teeth, and also for regulating certain body processes.

The coating process plays a crucial role in tablet coating and many of the issues or problems arising come from the process setup. The different variables that affect the film coating should be addressed and how these variables play a crucial role in the coating process. The equipment type for film coating is also tackled in the article.

Vitamin D is necessary for maintaining good health, but 40 to 75% of the world's population is deficient. The vitamin is not found in many foods. Fortified milk, eggs, fish and beef liver are some of the few containing vitamin D and even in these the amounts may be small.

Drying in the pharmaceutical industry involves the extraction of liquid and other liquid solvents from the materials or granules using air current or heat. Fluidized bed dryer is one of the equipment used to dry the granule particles using the FBD finger bag.

When people first think of tablet or pill presses they think pharmaceuticals, supplements, vitamins and minerals or just medicines. But tablet making machines can be used for other purposes.

药品生产质量管理规范 (GMP)是一个确保产品生产和控制符合质量标准的体系。其旨在最大限度降低无法通过测试最终产品规避的药物生产风险。药品生产质量管理规范为制造、测试和质量保证提供指导，确保食品或药品安全。许多国家立法规定食品、药品和医疗器械制造商必须遵循GMP程序，并制定属于自己的合规GMP指南。

This article covers general GMP procedures. Including QA staff must do a round of the plant area making sure that the plant adheres to the cGMP and fill up the checklist provided by the company. Head or In-charge personnel should review the plant audit and discuss this with the person in charge of the plant after which the audit report will be closed.