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A Mix–Up may be defined as:

• An unplanned combination of various compounds.
• A mistake brought about wrongly identifying one material for another.

A mix-up can be caused by bad judgement or lack of attention to detail, i.e., human error. It can also occur though poor communication between personnel.

A big factor in choosing your Rotary Tablet Press will be the batch sizes you intend to produce with it.

While it might seem that the machine with the most output should finish every batch size in first, the table below demonstrates that is not the case.

The larger the machine the more parts there are to clean meaning the higher the labour costs.

One of the major problems that the tablet manufacturing companies faces is tablet sticking. This problem occurs when the granulation sticks to the punch surface causing deformed tablets, which is very costly not only for the manufacturers but also for the formulators. One way to alleviate this problem is using analytical method as well as create screening processes. Authorities or field experts are also looking for ways to create analytical models to identify the solutions quickly for specific problems.

Tablet binders are one of the most essential elements in the formulation of a tablet. Because they promote cohesiveness, the binders, also called adhesives, help the other ingredients in a tablet to mix together. Tablet binders are used to turn powder to granules; this is achieved through the process of granulation. During granulation, powder substances are accumulated to form larger particles called granules.

Description: The term “Binding” is used when the tablet sticks to, takes hold or splits during the molding / pressing process.

The following is a brief operating and cleaning guide that can be used for most tablet de-dusting machines. It covers pre-start up, operation and cleaning, and lists some precautions that can be taken to help avoid contamination issues.

The design of tablets requires careful research and understanding especially with respect to the shape of the tablets. Even tiny variations can have a direct impact not only on the cost of production but also on patient’s acceptance, which can lead to either the success or failure of the product.

Here is a list of commonly used terms and there definitions. This it to help you understand and navigate our website more easily. We hope you find it useful.

If there is something that you feel needs adding to the list then please feel free to get in contact and we will add it.

It is time consuming and expensive for tablet manufacturers to inspect tooling equipment. That said, advancements in technology have made in-process inspections easier to carry out. Here we discuss some of the main technological developments that have facilitated an easier and less costly in-process inspection.

A drug is defined as a mixture of compounds used in the pharmaceutical industry to treat and prevent diseases. The different drug forms help health care providers to administer the drug safely. In this article LFA discusses the different forms of drug dosing and how best you can use them in your business.

Tablet Coating machines are equipment devices used to coat the tablet’s outer surface with a thin coating film.

Tablet packaging machines comes in different types and is categorized as follows

Tablet machines, also called as compressing machines or tablet presses, are the equipment used to compress the powder into its tablet form forming uniform size, shape and weight.

Granulation is the process whereby powder forms are bound together to form aggregates, which are called as granules. Granulation is important as it helps prevent the separation of the ingredients in the mixture as well as improves the flow of the properties of the mixture. It also changes the size of the particles resulting to improved compression and density of the powder mix.

At LFA over the last 7 years we have seen a glimpse into every type of use for a tablet press. Nowadays when someone asks us how to press glass, or metal, or even coffee granules we are no longer surprised. One that was new to us was the pigeon problem.

The process of sugar coating is rare in the pharmaceutical world recently. That said, knowing the problems that one can encounter would help in the event that sugar coating is needed and problems arise.

The rules have changed when it comes to development of products in the pharmaceutical, health and nutritional industry. As generic and branded companies in the industry struggle with new products while at the same time addressing the need of new patients, the companies must also meet the growing productivity demands in the manufacturing industry.