This is a frequently asked question on the TDP range. This range of single station pill press includes the TDP 1.5, TDP 5 and TDP 6s. The machines are very similar and the main distinction between them is the pressure that is exerted during tablet making.
Medicines are a go to whenever one experiences health problems. From over the counter medicines to prescriptions, these pills have become vital to our everyday lives. Due to the advancement in technology, two different forms are now available – tablets and capsules. For some time, tablets are quite popular way of taking in medication or supplements; later on however, consumers discover the effects of taking tablets.
The cup depth is the space between the punch tip and the lowest possible measurable area of a cup cavity. In order to form proper inspection and wear limits of the tooling equipment, it is important that one should know about it, and how premature wear can affect the tablet.
In the pharmaceutical world, there are certain medicine products that needs certain specific temperature in order to maintain its efficiency, structure and safety.
Coenzyme Q10, often called CoQ10, is a compound that occurs naturally in the human body. All the cells of the body produce this enzyme, which helps to produce energy for normal cell maintenance and growth.
The presence of unwanted materials such as dust and particles during the manufacturing and transportation time is called contamination. The term contaminants includes any unwanted matter that is found in the product. These contaminants affect the quality of the product or the process.
One of the major problems with sterile manufacturing is the possibility of contamination. The cleanroom area is one of the hardest places to maintain sterile or clean and is the major source of contamination.
Changing the tablet manufacturing process can lead to better and more improved quality products as well as cost efficiency for the company. By communicating with one’s tooling vendor and taking into consideration the right material type, one can overcome the many problems that tablet companies are facing today.
There are varieties of problems that face the pharmaceutical world, some of which we will be discussing as well as solutions that would help solve these problems.
- Overwetting of the tablets/Surface pitting. This is where suspension droplets hit the still wet tablet and the drying air does not dry it enough.
- Physical damages overloading or unloading operation.
- Poor tablet design – flat surfaces.
- Spray Drying. The suspension droplets hit the tablet after the moisture has been removed. This leads to the poor adherence of the coat
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Tablet defects occur for a variety of reasons, but many can easily be avoided. To address defects, technicians involved in tabletting must have a full understanding of both the tabletting process and the materials used. Adequate training in the setting up and use of the machines is vital if the technician is to have the necessary skills to be able to fix equipment and minimize problems in production.
In the tablet manufacturing industry, the most common problem that they encounter is what one would call as “Sticking”. This happens when the granulation sticks to the tool face, which results to sticky products and failure of the presses to compress the tablets. This is a big problem for manufacturers as the sticking goes unnoticed and only seen once the item is in production.
The nonionic detergents are the type of cleaning agent used in the pharmaceutical industry as it helps sanitize and protect the equipment in order to prevent poor quality and thus uphold the quality of the product.
It is time consuming and expensive for tablet manufacturers to inspect tooling equipment. That said, changes and advancement in technology makes it easier to doin-processinspections. Below is a brief on the improvement in technology to improvein-processinspection.
The rules have changed when it comes to development of products in the pharmaceutical, health and nutritional industry.
Although LFA Tablet Presses does not sell capsules or capsule fillers we do feel that it is very important to provide our customers with as much information as possible. In this article we discuss the types of capsules and the their potential applications.
The use of scoring on tablets has long been implemented by the manufacturing industry mainly to prevent stress fractures but later on for more considerations that are primarily aesthetic. Bisects are different as they present a challenge to manufacturers as they can affect the tablets.
The tablet land is a slight level surface that is vertical to the tablet’s boundary creating a junction between the boundary and the cup of the tablet. There are three main reasons why one would incorporate a land into the tablet’s design.
- Increase the strength of the punch edge
- Increase the wear of the punch cup inner edges
- Lower the relentlessness of the nicks on the edges of the punch
Binders are chemical compounds that have an adhesive property. They bind the drug and excipient together and provide it with extra strength. Binders can also form intergranular bonds that fuse together and form a binder bridge between granules adhering to each other. The bridges may result from the melting or softening of the binder during the compression process.