A wire mesh on a granulator

Different Wire Mesh Sizes And Its Conversions

In the pharmaceutical industry, sieves and screens are regularly used to determine the size of raw materials. The most common way to measure the sieves and screens is with meshes. On average, about 40 to 400 sieves are used in the industry, especially during the milling and sifting of raw materials.

Getting the mesh size correct for your particular blend is really critical. It will determine how the excipients mix together during the mixing process, how the dry lubricants and anti-caking agents react with the binders and, ultimately, how the mix presses in the tablet or pill press that you are using.

A mesh shows the available opening in one linear inch of a screen or sieve; a 10-mesh sieve has 10 openings, whilst, a 300-mesh sieve will have 300 available openings in a linear inch. The fineness of the screen or sieve will depend on the wire width. A wire that is used for a 10-mesh sieve is thicker than one that is used for a 60-mesh sieve;, a thin wire will not work for a thick sieve and a thick wire won’t be used to make a fine sieve.

For a material to have fine particles, it is important to use a fine sieve with small openings. To determine the fineness of the sieve, one should take into consideration the size of the mesh. When the mesh size increases and the pore decreases, the fineness of the sieve increases.

Conversion Table for Mesh to Microns and Inches

U.S. MESH MICRONS INCHES MILIMETERS
3 6730 0.2650 6.730
4 4760 0.1870 4.730
5 4000 0.1570 4.000
6 3360 0.1320 3.360
7 2830 0.1110 2.830
8 2380 0.0937 2.380
10 2000 0.0787 2.000
12 1680 0.0661 1.680
14 1410 0.0555 1.410
16 1190 0.0469 1.190
18 1000 0.0394 1.000
20 841 0.0331 0.841
25 707 0.0280 0.707
30 595 0.0232 0.595
35 500 0.0197 0.500
40 400 0.0165 0.400
45 354 0.0138 0.354
50 297 0.0117 0.297
60 250 0.0098 0.250
70 210 0.083 0.210
80 177 0.0070 0.177
100 149 0.0059 0.149
120 125 0.0049 0.125
140 105 0.0041 0.105
170 88 0.0035 0.088
200 74 0.0029 0.074
230 63 0.0024 0.063
270 53 0.0021 0.053
325 44 0.0017 0.044
400 37 0.0015 0.037

There is no standard formula to convert mesh to micron and vice-versa. Below is a conversion formula that might help to provide an approximate value on the conversion of the mesh to micron and vice-versa.

Mesh x Micron = 14900 (Approximate)

Micron = 14900/Mesh or

Mesh = 14900/Micron

As this is only an estimate, remember to leave room for error. The formula is helpful if one wants to have an approximate value for 50 to 400 mesh.

Follow this formula for converting mesh and inch:

Inch= 0/6/mesh

Mesh = 0.6/inch

Mesh Size Micron % Variation from Original
Original Calculated
50 297 297 0.3
60 250 248.3 -0.7
70 210 212.8 1.3
80 177 186 5.1
100 149 149 0.0
120 125 124 -0.8
140 105 106 1.0
170 88 88 0.0
200 74 74.5 0.7
230 63 64.7 2.7
270 53 55.1 4.0
325 44 45.8 4.1
400 37 37.25 0.7

Determining the Mesh Size of Different Screen Size

To obtain the mesh size of any screen type, follow these simple steps:

  • Mark the sieve about 1 inch using a marker and a scale
  • To be more accurate, start measuring from the center of the wire
  • Start counting the holes in one linear inch

Example: if there were 40 holes in one linear inch, it would be 40-mesh in the sieve.

Related Articles

Rapid Mix Granulator – Operation and Cleaning Guide

Rapid Mix Granulator – Operation and Cleaning Guide

A rapid mix granulator is a multi-purpose mixer/processor equally suitable for high speed dispersion of dry powders (including effervescent powders) and their granulation with aqueous or organic solvents. The equipment is designed to achieve rapid mixing and the formation of consistent granules required for the production of high quality pharmaceutical tablets for solid dosage forms of medication. Good mixing and control of granule size leads to fast tableting speeds and high quality products with low rejection rate.

The Mechanism Of Granulation - Formation And Methods

The Mechanism Of Granulation - Formation And Methods

Granulation is the process whereby powder forms are bound together to form aggregates, which are called as granules. Granulation is important as it helps prevent the separation of the ingredients in the mixture as well as improves the flow of the properties of the mixture. It also changes the size of the particles resulting to improved compression and density of the powder mix.

Tray dryers for drying wet, sticky or granulated products

Tray dryers for drying wet, sticky or granulated products

Tray dryers are devices used to dry wet products of chemicals, powders and crude drugs. The simplest way to explain a tray dryer is a cabinet that has a heater at the bottom or a laboratory oven. The oven has little to no value because control is non-existent for humidity and heat transferred.

© 2024 LFA Machines Oxford LTD. All Rights Reserved.